| ncRNA name | mmu-miR-150 |
| ncRNA Category | miRNA |
| Disease name | age-related macular degeneration (AMD) |
| Species | Mus musculus |
| Tissues/Cell_line | macrophages; RPE-choroid complex |
| Methods | microarray, RNA-seq, lipidomic analysis, ELISA |
| Expression pattern | up-regulated |
| Functional description | miR-150 directly targets stearoyl-CoA desaturase-2, which coordinates macrophage-mediated inflammation and pathologic angiogenesis, as seen in AMD, in a VEGF-independent manner. |
| PubMed ID | 29618664 |
| Year | 2018 |
| Title | Macrophage microRNA-150 promotes pathological angiogenesis as seen in age-related macular degeneration. |
| Drug-related ncRNA | NO |
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